CYTOTOXIC METABOLITES FROM THE OKINAWAN ASCIDIAN DIPLOSOMA VIRENS

Cytotoxic Metabolites from the Okinawan Ascidian Diplosoma virens

The unstable isomeric compounds Plate Covers 5-hydroxy-7-prop-2-en-(E)-ylidene-7,7adihydro-2H-cyclopenta[b]pyran-6-one (1) and 5-hydroxy-7-prop-2-en-(Z)-ylidene-7,7adihydro-2H-cyclopenta[b]pyran-6-one (2), previously described as antimicrobialmetabolites from the sponge Ulosa sp., were isolated and identified as major componentsof the ascidian Dipl

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A Mouse Model Suggests That Heart Failure and Its Common Comorbidity Sleep Fragmentation Have No Synergistic Impacts on the Gut Microbiome

Heart failure (HF) is a common condition associated with a Utensils high rate of hospitalizations and adverse outcomes.HF is characterized by impairments of either the cardiac ventricular filling, ejection of blood capacity or both.Sleep fragmentation (SF) involves a series of short sleep interruptions that lead to fatigue and contribute to cogniti

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